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What is anaphylaxis?
In the early 1900's, when vaccination was still a novelty, a group of scientists were trying to induce immunity in dogs ('prophylaxis'). When subsequent doses of certain proteins led to death, rather than immunity, the term 'anaphylaxis' (the opposite of 'prophylaxis') was coined. While there is no universally accepted definition of anaphylaxis (Anna-fill-axis), most physicians would agree that it is a life-threatening allergic reaction to a specific trigger (food, insect sting, medication, exercise, and latex) in a person who has become sensitized. There is disagreement, however, about the constellation of symptoms by which it can be recognized.
How common is anaphylaxis?
A conservative estimate is that 2% of the population (approximately 600,000 Canadians) may be affected by potentially life-threatening allergies. The incidence may be higher in children and it has increased dramatically in the last decade.
What is the difference between anaphylactic and anaphylactoid?
Anaphylactic and anaphylactoid reactions are similar in their clinical presentation and treatment. The only difference is the chemical reactions that are taking place. Anaphylactic reactions are mediated by IgE (an immunoglobulin) and anaphylactoid reactions are not.
Last date modified on Friday, December 20, 2002
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